OXERVATE® is a prescription eye drop solution used to treat a condition called neurotrophic keratitis. OXERVATE is safe and effective in children two years of age and older.
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How to use OXERVATE®

This dosing and administration overview will help you understand how to use OXERVATE®.

ADMINISTRATION

Learn how to dose and apply OXERVATE properly

Applying OXERVATE is a multistep process using the materials in the Delivery System Kit and should only be done according to the Instructions for Use. A full transcript of this video is available here.

Dosing

Dosing schedule

Use OXERVATE exactly as your doctor tells you.
Start in the morning, or as directed by your doctor.

Use 1 drop of in your affected eye, or eyes, 6 times each day, about 2 hours apart. Continue your treatment for 8 weeks.
Use 1 drop of in your affected eye, or eyes, 6 times each day, about 2 hours apart. Continue your treatment for 8 weeks.

Wait 15 minutes between applying OXERVATE and using other drops, ointments or gels. Remove contact lenses 15 minutes before using OXERVATE and wait 15 after using before reinserting them

When getting ready to apply OXERVATE, remember the
15-minute reminders

If you use any other eye drops

  • Make sure to use other eye drops at least 15 minutes before or after using OXERVATE

If you use any other eye ointment, gel, or thick eye drop

  • Make sure to use OXERVATE first, then wait at least 15 minutes before using the other eye ointment, gel, or drop

If you wear contact lenses in your affected eye(s)

  • Remove them before using OXERVATE. Wait 15 minutes after using before reinserting them

If you miss a dose of OXERVATE, take your next dose at your scheduled time and do not take an extra dose to make up for the missed one.

Do not use other eye medicines without talking to your doctor.

Talk to your doctor first before you stop using OXERVATE.

If you have any questions about how to use OXERVATE, ask your doctor or pharmacist.

OXERVATE comes with a Delivery System Kit containing everything you need to use it.

DELIVERY SYSTEM KIT

How to use

OXERVATE is supplied in an insulated pack, in weekly cartons containing 7 multiple-dose vials. This may include either frozen and/or refrigerated gel packs or, in some cases, dry ice. OXERVATE is supplied with an accompanying Delivery System Kit. The Delivery System Kit will have medical devices for withdrawing and using OXERVATE. You will receive both the OXERVATE weekly carton(s) and the Delivery System Kit from the pharmacy.

Important:

  • OXERVATE is for use in the eye
  • Do not shake the OXERVATE vial
  • Use OXERVATE with the vial adapters, sterile disinfectant wipes, and pipettes that come with your Delivery System Kit
Getting OXERVATE

OXERVATE
Weekly Carton contains

7 multiple-dose vials of OXERVATE(1 vial per day of the week)

Delivery System Kit contains

7 vial adapters (+1 extra)

42 pipettes (+3 extra)

42 sterile
disinfectant wipes (+3 extra)

Use the Dose Recording Card included in your Delivery System Kit to:

  • Track your 6 doses per day
  • Write down the date you start a new weekly supply
  • Note the time you opened a vial (when you connect the vial adapter to the vial) during the week

  • Track your 6 doses per day
  • Write down the date you start a new weekly supply
  • Note the time you opened a vial (when you connect the vial adapter to the vial) during the week

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ALL FIELDS REQUIRED

Important Safety Information

Before you use OXERVATE, tell your doctor about all of your medical conditions, including if you:

  • have an infection in your eye. If you get an eye infection while using OXERVATE, talk to your doctor right away.
  • are pregnant or plan to become pregnant. It is not known if OXERVATE will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if OXERVATE passes into your breast milk. Talk to your doctor about the best way to feed your baby if you use OXERVATE.

How should I use OXERVATE?

  • Use 1 drop of OXERVATE in the affected eye or both eyes if needed, 6 times each day, about 2 hours apart starting in the morning. Continue your treatment for 8 weeks.
  • If you use any other eye drops, wait at least 15 minutes before or after using OXERVATE. This will help to avoid one eye drop diluting the other eye drop.
  • If you also use an eye ointment or gel or an eye drop that is thick, use OXERVATE first, and then wait at least 15 minutes before using the other eye ointment, gel, or drops.
  • If you wear contact lenses in your affected eye or both eyes remove them before using OXERVATE and wait 15 minutes after using OXERVATE before reinserting them.
  • Do not use other eye medicines without talking to your doctor.
  • Talk to your doctor first before you stop using OXERVATE.

What should I avoid while using OXERVATE?

  • Your vision may be blurred for a short time after using OXERVATE. If this happens, wait until your vision clears before you drive or use machines.

What are the possible side effects of OXERVATE?

  • The most common side effect of OXERVATE is eye pain, enlarged blood vessels in the white of the eyes, swelling of the eye, and increase of tears.

Tell your doctor if you have any side effects that bother you. These are not all the possible side effects of OXERVATE.

For more information about OXERVATE talk to your healthcare provider or pharmacist.

To report ADVERSE REACTIONS, contact Dompé U.S. Inc. at 1-833-366-7387 or FDA at
1-800-FDA-1088 or www.fda.gov/medwatch.

What is OXERVATE?

  • OXERVATE is a prescription eye drop solution used to treat a condition called neurotrophic keratitis.

Please see full Prescribing Information and Patient Information for OXERVATE.