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When your doctor prescribes OXERVATE® you’ll be supported every step of the way—from accessing treatment and receiving deliveries, to learning how to properly prepare and apply OXERVATE.

Learn how to use. Watch video

About Oxervate

The only FDA-approved prescription eye drop to treat people with neurotrophic keratitis

About NK

What is neurotrophic keratitis?

Neurotrophic keratitis, also referred to as neurotrophic keratopathy, or “NK,” is an eye disease caused by damage to the corneal nerves that leads to breakdown of the cornea.

If not treated, it can lead to a corneal ulcer (an open sore on the cornea), scarring, or even vision loss.

How to Use

Preparing for treatment

Use this dosing and administration overview to understand what to expect from treatment with OXERVATE or refresh your memory on how to use it.

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Important Safety Information


  • OXERVATE is a prescription eye drop solution used to treat a condition called neurotrophic keratitis.

Before you use OXERVATE, tell your doctor about all of your medical conditions, including if you:

  • have an infection in your eye. If you get an eye infection while using OXERVATE, talk to your doctor right away.
  • are pregnant or plan to become pregnant. It is not known if OXERVATE will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if OXERVATE passes into your breast milk. Talk to your doctor about the best way to feed your baby if you use OXERVATE.

How should I use OXERVATE?

  • Use 1 drop of OXERVATE in the affected eye or both eyes if needed, 6 times each day, about 2 hours apart starting in the morning. Continue your treatment for 8 weeks.
  • If you use any other eye drops, wait at least 15 minutes before or after using OXERVATE. This will help to avoid one eye drop diluting the other eye drop.
  • If you also use an eye ointment or gel or an eye drop that is thick, use OXERVATE first, and then wait at least 15 minutes before using the other eye ointment, gel, or drops.
  • If you wear contact lenses in your affected eye or both eyes remove them before using OXERVATE and wait 15 minutes after using OXERVATE before reinserting them.
  • Do not use other eye medicines without talking to your doctor.
  • Talk to your doctor first before you stop using OXERVATE.

What should I avoid while using OXERVATE?

  • Your vision may be blurred for a short time after using OXERVATE. If this happens, wait until your vision clears before you drive or use machines.

What are the possible side effects of OXERVATE?

  • The most common side effect of OXERVATE is eye pain, enlarged blood vessels in the white of the eyes, swelling of the eye, and increase of tears.

Tell your doctor if you have any side effects that bother you. These are not all the possible side effects of OXERVATE.

For more information about OXERVATE talk to your healthcare provider or pharmacist.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1‑800‑FDA‑1088. You can also contact Dompé U.S. Inc. at 1‑833‑366‑7387.

Please see full Prescribing Information and Patient Information for OXERVATE.