OXERVATE® is a prescription eye drop solution used to treat a condition called neurotrophic keratitis. OXERVATE is safe and effective in children two years of age and older.
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Frequently asked questions

What is OXERVATE®?

OXERVATE is a prescription eye drop solution used to treat a condition called neurotrophic keratitis. OXERVATE is safe and effective in children two years of age and older.

What are the possible side effects of OXERVATE?

The most common side effects of OXERVATE are eye pain, corneal deposits, feeling of having something in the eye, enlarged blood vessels in the white of the eyes, swelling of the eye, sensitivity to light, increase of tears, and headache.

These are not all the possible side effects of OXERVATE.

Tell your doctor if you have any side effects that bother you or do not go away.

Can OXERVATE be used by contact lens wearers?

Yes, OXERVATE can be used by contact lens wearers.

If you wear contact lenses in your affected eye or both eyes, remove them before using OXERVATE and wait 15 minutes after using OXERVATE before reinserting them.

How can I get OXERVATE?

OXERVATE is a prescription medication, so a doctor must prescribe it to a patient. Once a doctor has determined a prescription would be appropriate, a patient may elect to enroll in Dompé CONNECT to Care—a patient support program provided by the manufacturer to help with insurance verification, prior authorizations, financial assistance, and general questions.

Do I need to refrigerate my OXERVATE upon receiving my delivery?

Yes, the OXERVATE weekly carton(s) must be stored at 36 °F to 46 °F (2 °C to 8 °C) no later than 5 hours from when you receive the medicine from your pharmacy.

Do not freeze.

What is neurotrophic keratitis (NK)?

Neurotrophic keratitis, or “NK,” is an eye disease that may be caused by damage to the corneal nerves. This damage may lead to poor healing and degeneration of the cornea.

If not treated, it may lead to a corneal ulcer (an open sore in the cornea).

What causes neurotrophic keratitis (NK)?

NK may occur when the nerves of the cornea are damaged.

This damage may lead to poor healing of the corneal surface. When your corneal nerves are damaged, your cornea may have a lack of feeling and may be unable to send normal signals to your brain.

As a result, the corneal surface may break down, which may lead to NK.

What are the symptoms of neurotrophic keratitis (NK)?

Neurotrophic keratitis (NK) may cause different symptoms in different people. In the early stages, symptoms may range from dryness, sensitivity to light, reduced blinking, or blurry vision. In later stages of disease, persistent damage to or ulceration of the cornea may occur—but some people may not complain of symptoms at all due to the lack of feeling in the cornea.

How can I find out if I have neurotrophic keratitis (NK)?

Neurotrophic keratitis (NK) is a rare disease that requires professional diagnosis. Only an eye care professional will be able to determine if an individual has NK.

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ALL FIELDS REQUIRED

Important Safety Information

Before you use OXERVATE, tell your doctor about all of your medical conditions, including if you:

  • have an infection in your eye. If you get an eye infection while using OXERVATE, talk to your doctor right away.
  • are pregnant or plan to become pregnant. It is not known if OXERVATE will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if OXERVATE passes into your breast milk. Talk to your doctor about the best way to feed your baby if you use OXERVATE.

How should I use OXERVATE?

  • Use 1 drop of OXERVATE in the affected eye or both eyes if needed, 6 times each day, about 2 hours apart starting in the morning. Continue your treatment for 8 weeks.
  • If you use any other eye drops, wait at least 15 minutes before or after using OXERVATE. This will help to avoid one eye drop diluting the other eye drop.
  • If you also use an eye ointment or gel or an eye drop that is thick, use OXERVATE first, and then wait at least 15 minutes before using the other eye ointment, gel, or drops.
  • If you wear contact lenses in your affected eye or both eyes remove them before using OXERVATE and wait 15 minutes after using OXERVATE before reinserting them.
  • Do not use other eye medicines without talking to your doctor.
  • Talk to your doctor first before you stop using OXERVATE.

What should I avoid while using OXERVATE?

  • Your vision may be blurred for a short time after using OXERVATE. If this happens, wait until your vision clears before you drive or use machines.

What are the possible side effects of OXERVATE?

  • The most common side effect of OXERVATE is eye pain, enlarged blood vessels in the white of the eyes, swelling of the eye, and increase of tears.

Tell your doctor if you have any side effects that bother you. These are not all the possible side effects of OXERVATE.

For more information about OXERVATE talk to your healthcare provider or pharmacist.

To report ADVERSE REACTIONS, contact Dompé U.S. Inc. at 1-833-366-7387 or FDA at
1-800-FDA-1088 or www.fda.gov/medwatch.

What is OXERVATE?

  • OXERVATE is a prescription eye drop solution used to treat a condition called neurotrophic keratitis.

Please see full Prescribing Information and Patient Information for OXERVATE.