
Mechanism of Action
MOA
OXERVATE is a recombinant human nerve
growth factor (rhNGF)1
Nerve growth factor (NGF) is an endogenous protein involved in the differentiation and maintenance of neurons, which acts through specific high-affinity (ie, TrkA) and low-affinity (ie, p75NTR) nerve growth factor receptors in the anterior segment of the eye to support corneal innervation and integrity.1